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Author: Brian Wu PhD. MD Candidate, Keck School of Medicine, Los Angeles, USA; Chief Editor: Hon A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand, February 2016.
Ascher syndrome is a rare condition characterised by persistent swelling of the lip and eyelids and sometimes by nontoxic thyroid enlargement.
It was first described in 1920 by Dr. Ascher, an ophthalmologist in Prague.
Ascher syndrome appears to have no prevalence by gender, age, sex or geographical area.
The exact cause of Ascher syndrome is unknown. If acquired, it is usually due to trauma. If congenital, it stems from some developmental anomaly.
The three salient characteristics of Ascher syndrome include:
Staging of blepharochalasis is as follows:
Associated signs and symptoms of this condition include:
Angioedema causing eyelid or lip oedema is not persistent, and last hours to a few days. Persistent eyelid oedema is sometimes a feature of phymatous rosacea. Persistent lip swelling arises in granulomatous cheilitis and other forms of orofacial granulomatosis.
Treatment for Ascher syndrome can include surgery:
With surgical treatment, prognosis is good and functional and aesthetic improvement can be achieved.
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